TY  - JOUR
A1  - Heyer, Laurie J.
A1  - Kruglyak, Semyon
A1  - Yooseph, Shibu
T1  - Exploring Expression Data: Identification and Analysis of Coexpressed Genes
Y1  - 1999/11/01 
JF  - Genome Research 
JO  - Genome Research 
SP  - 1106 
EP  - 1115 
DO  - 10.1101/gr.9.11.1106 
VL  - 9 
IS  - 11 
UR  - http://genome.cshlp.org/content/9/11/1106.abstract 
N2  - Analysis procedures are needed to extract useful information from the large amount of gene expression data that is becoming available. This work describes a set of analytical tools and their application to yeast cell cycle data. The components of our approach are (1) a similarity measure that reduces the number of false positives, (2) a new clustering algorithm designed specifically for grouping gene expression patterns, and (3) an interactive graphical cluster analysis tool that allows user feedback and validation. We use the clusters generated by our algorithm to summarize genome-wide expression and to initiate supervised clustering of genes into biologically meaningful groups. 
ER  -