@article{White01101999, author = {White, Peter S. and Sulman, Erik P. and Porter, Christopher J. and Matise, Tara C.}, title = {A Comprehensive View of Human Chromosome 1}, volume = {9}, number = {10}, pages = {978-988}, year = {1999}, doi = {10.1101/gr.9.10.978}, abstract ={Comprehensive representations of human chromosomes combining diverse genomic data sets, localizing expressed sequences, and reflecting physical distance are essential for disease gene identification and sequencing efforts. We have developed a method (CompView) for integrating genomic information derived from available cytogenetic, genetic linkage, radiation hybrid, physical, and transcript-based mapping approaches. CompView generates chromosome representations with substantially higher resolution, coverage, and integration than current maps of the human genome. The CompView process was used to build a representation of human chromosome 1, yielding a map with >13,000 unique elements, an effective resolution of 910 kb, and a marker density of 50 kb. CompView creates comprehensive and fully integrated depictions of a chromosome's clinical, biological, and structural information.}, URL = {http://genome.cshlp.org/content/9/10/978.abstract}, eprint = {http://genome.cshlp.org/content/9/10/978.full.pdf+html}, journal = {Genome Research} }