RT Journal A1 Dear, Simon A1 Durbin, Richard A1 Hillier, LaDeana A1 Marth, Gabor A1 Thierry-Mieg, Jean A1 Mott, Richard T1 Sequence Assembly with CAFTOOLS JF Genome Research JO Genome Research YR 1998 FD March 01 VO 8 IS 3 SP 260 OP 267 DO 10.1101/gr.8.3.260 UL http://genome.cshlp.org/content/8/3/260.abstract AB Large-scale genomic sequencing requires a software infrastructure to support and integrate applications that are not directly compatible. We describe a suite of software tools built around the Common Assembly Format (CAF), a comprehensive representation of a sequence assembly as a text file. These tools form the backbone of sequencing informatics at the Sanger Centre and the Genome Sequencing Center. The CAF format is intentionally flexible, and our Perl and C libraries, which parse and manipulate it, provide powerful tools for creating new applications as well as wrappers to incorporate other software. The tools are available free by anonymous FTP from ftp://ftp.sanger.ac.uk/pub/badger/.