TY - JOUR A1 - Ivens, Alasdair C. A1 - Lewis, Sharon M. A1 - Bagherzadeh, Azadeh A1 - Zhang, Linglan A1 - Chan, Ho M. A1 - Smith, Deborah F. T1 - A Physical Map of the Leishmania majorFriedlin Genome Y1 - 1998/02/01 JF - Genome Research JO - Genome Research SP - 135 EP - 145 DO - 10.1101/gr.8.2.135 VL - 8 IS - 2 UR - http://genome.cshlp.org/content/8/2/135.abstract N2 - An extensive physical map of the Leishmania majorFriedlin genome has been assembled by the combination of fingerprint analysis of a shuttle vector cosmid library and probe hybridization. The integrated data obtained for 9004 fingerprinted clones and 974 probes have placed 91.2% of the 33.58-Mb genome into contigs representing each of the 36 chromosomes. This first-generation map has already provided a suitable framework for both high-throughput DNA sequencing and functional studies of the L. major parasite. ER -