RT Journal A1 Sanger Centre, The A1 Washington University Genome Sequencing Center, The T1 Toward a Complete Human Genome Sequence JF Genome Research JO Genome Research YR 1998 FD November 01 VO 8 IS 11 SP 1097 OP 1108 DO 10.1101/gr.8.11.1097 UL http://genome.cshlp.org/content/8/11/1097.abstract AB We have begun a joint program as part of a coordinated international effort to determine a complete human genome sequence. Our strategy is to map large-insert bacterial clones and to sequence each clone by a random shotgun approach followed by directed finishing. As of September 1998, we have identified the map positions of bacterial clones covering ∼860 Mb for sequencing and completed >98 Mb (∼3.3%) of the human genome sequence. Our progress and sequencing data can be accessed via the World Wide Web (http://webace.sanger.ac.uk/HGP/ orhttp://genome.wustl.edu/gsc/).