TY  - JOUR
A1  - Rosenberg, Marjorie
A1  - Hui, Lester
A1  - Ma, Junli
A1  - Nusbaum, Harris C.
A1  - Clark, Kevin
A1  - Robinson, Louise
A1  - Dziadzio, Laura
A1  - Swain, Pamela M.
A1  - Keith, Tim
A1  - Hudson, Thomas J.
A1  - Biesecker, Leslie G.
A1  - Flint, Jonathan
T1  - Characterization of Short Tandem Repeats from Thirty-One Human Telomeres
Y1  - 1997/09/01 
JF  - Genome Research 
JO  - Genome Research 
SP  - 917 
EP  - 923 
DO  - 10.1101/gr.7.9.917 
VL  - 7 
IS  - 9 
UR  - http://genome.cshlp.org/content/7/9/917.abstract 
N2  - Completion of genetic and physical maps requires markers from the ends (telomeres) of every human chromosome. We have searched for short tandem repeats (microsatellites) in cosmid and P1 clones and generated 661 sequence-tagged sites (STS) from the terminal 300 kb of 31 human chromosome ends. PCR assays were successfully designed for 58 microsatellites and mapped both genetically and on radiation hybrids (RHs) to confirm their telomeric location. Sequence analysis revealed marked variation in sequence composition, consistent with the hypothesis that even very highly GC-rich chromosome bands (the T bands) are not homogenous. The STSs that we have generated will be a necessary resource for the construction of physical maps of these complex regions of the genome.[Information about the microsatellites is available electronically at http://www.cshl.org/gr and sequence has been deposited in the Genome Database (GDB).] 
ER  -