TY  - JOUR
A1  - Greinwald, John H.
A1  - Scott, Daryl A.
A1  - Marietta, Jacquie R.
A1  - Carmi, Rivka
A1  - Manaligod, Jose
A1  - Ramesh, Arabandi
A1  - Zbar, Ross I.S.
A1  - Kraft, Michelle L.
A1  - Elbedour, Khalil
A1  - Yairi, Yael
A1  - Musy, Maurice
A1  - Skvorak, Anne B.
A1  - Van Camp, Guy
A1  - Srisailapathy, C.R. Srikumari
A1  - Lovett, Michael
A1  - Morton, Cynthia C.
A1  - Sheffield, Val C.
A1  - Smith, Richard J.H.
T1  - Construction of P1-Derived Artificial Chromosome and Yeast Artificial Chromosome Contigs Encompassing the DFNB7 andDFNB11 Region of Chromosome 9q13–21
Y1  - 1997/09/01 
JF  - Genome Research 
JO  - Genome Research 
SP  - 879 
EP  - 886 
DO  - 10.1101/gr.7.9.879 
VL  - 7 
IS  - 9 
UR  - http://genome.cshlp.org/content/7/9/879.abstract 
N2  - 
DFNB7 and DFNB11, two loci for autosomal recessive nonsyndromic hearing loss (ARNSHL), have been mapped to chromosome 9q13–21 in separate consanguineous families. Using a radiation hybrid map, we have determined the correct marker order in the DFNB7/11 region and have demonstrated that theDFNB11 locus resides within a redefined DFNB7interval. The gene(s) responsible for ARNSHL at these loci resides within an ∼1 cM interval bounded by markers D9S1806(centromeric) and D9S769 (telomeric). A recently discovered Indian family confirms the new telomeric boundary. To assist in the identification and cloning of candidate genes, YAC and PAC contigs were constructed. A total of 19 YAC and 23 PAC clones were utilized to span the affected region and ensure double coverage throughout. Twenty-two previously published STSs and 21 new STSs were used to determine marker order and confirm the integrity of the contig. Using a positional cloning strategy we have identified three cochlear expressed genes that map to the DFNB7/11 interval. 
ER  -