TY - JOUR A1 - Bihoreau, Marie Thérèse A1 - Gauguier, Dominique A1 - Kato, Norihiro A1 - Hyne, Gina A1 - Lindpaintner, Klaus A1 - Rapp, John P. A1 - James, Michael R. A1 - Lathrop, G. Mark T1 - A Linkage Map of the Rat Genome Derived from Three F2 Crosses Y1 - 1997/05/01 JF - Genome Research JO - Genome Research SP - 434 EP - 440 DO - 10.1101/gr.7.5.434 VL - 7 IS - 5 UR - http://genome.cshlp.org/content/7/5/434.abstract N2 - We report the construction of a dense linkage map of the rat genome integrating 767 simple sequence length polymorphism markers, combined over three crosses with high rates of polymorphism. F2 populations from WKY × S (n = 159), BN × S (n = 91), and BN × GK (n = 139) were selected and genotyped for combinations of microsatellite markers. The loci define 21 linkage groups corresponding to the 20 rat autosomal chromosomes and the X chromosome. The map spans a genetic length of 1998 cM. This combined linkage map should facilitate the advancement of genetic studies for a wide variety of rat models characterized for complex phenotypes. ER -