TY - JOUR A1 - Nagaraja, R A1 - MacMillan, S A1 - Kere, J A1 - Jones, C A1 - Griffin, S A1 - Schmatz, M A1 - Terrell, J A1 - Shomaker, M A1 - Jermak, C A1 - Hott, C A1 - Masisi, M A1 - Mumm, S A1 - Srivastava, A A1 - Pilia, G A1 - Featherstone, T A1 - Mazzarella, R A1 - Kesterson, S A1 - McCauley, B A1 - Railey, B A1 - Burough, F A1 - Nowotny, V A1 - D'Urso, M A1 - States, D A1 - Brownstein, B A1 - Schlessinger, D T1 - X chromosome map at 75-kb STS resolution, revealing extremes of recombination and GC content. Y1 - 1997/03/01 JF - Genome Research JO - Genome Research SP - 210 EP - 222 DO - 10.1101/gr.7.3.210 VL - 7 IS - 3 UR - http://genome.cshlp.org/content/7/3/210.abstract N2 - A YAC/STS map of the X chromosome has reached an inter-STS resolution of 75 kb. The map density is sufficient to provide YACs or other large-insert clones that are cross-validated as sequencing substrates across the chromosome. Marker density also permits estimates of regional gene content and a detailed comparison of genetic and physical map distances. Five regions are detected with relatively high G + C, correlated with gene richness; and a 17-Mb region with very low recombination is revealed between the Xq13.3 [XIST] and Xq21.3 XY homology loci. ER -