@article{Sonstegard01011997, author = {Sonstegard, T S and Abel Ponce de León, F and Beattie, C W and Kappes, S M}, title = {A chromosome-specific microdissected library increases marker density on bovine chromosome 1.}, volume = {7}, number = {1}, pages = {76-80}, year = {1997}, doi = {10.1101/gr.7.1.76}, abstract ={Genetic resolution of bovine chromosome 1 (BTA1) linkage group was significantly increased by screening for microsatellite clones a microdissected library constructed from a bovine cell line carrying a t(1;29) translocation. Eighty-five percent of the microsatellites (ms) (46/54) identified were informative in the USDA/MARC mapping population, and 96% of these ms (44/46) linked to BTA1 (LOD > 3.0). When merged with 40 existing BTA1 markers the genetic map spanned 153.8 cM (sex-averaged interval, 1.9 cM). The fourfold improvement in marker density of BTA1 provides a genetic map that enhances mapping of quantitative trait loci and implementation of marker assisted selection.}, URL = {http://genome.cshlp.org/content/7/1/76.abstract}, eprint = {http://genome.cshlp.org/content/7/1/76.full.pdf+html}, journal = {Genome Research} }