RT Journal A1 Byrd, P J A1 Stankovic, T A1 McConville, C M A1 Smith, A D A1 Cooper, P R A1 Taylor, A M T1 Identification and analysis of expression of human VACM-1, a cullin gene family member located on chromosome 11q22-23. JF Genome Research JO Genome Research YR 1997 FD January 01 VO 7 IS 1 SP 71 OP 75 DO 10.1101/gr.7.1.71 UL http://genome.cshlp.org/content/7/1/71.abstract AB We have localized the human homolog of the rabbit vasopressin-activated calcium-mobilizing receptor VACM-1 to a region close to the gene for ataxia telangiectasia ATM on chromosome 11q22-23. We have determined the complete amino acid sequence of the human Hs-VACM-1 protein, which is 780 amino acids long. The human and rabbit sequences are highly conserved, differing at only seven amino acids. Northern analysis of the human gene showed expression in a wide range of human tissues. The Hs-VACM-1 gene has homology with the Caenorhabditis elegans gene Ce-cul-5, a member of a family of cullin genes that are involved in cell cycle regulation and that might, when mutated, contribute to tumor progression.