@article{McGuire01041996,
author = {McGuire, R E and Jordan, S A and Braden, V V and Bouffard, G G and Humphries, P and Green, E D and Daiger, S P}, 
title = {Mapping the RP10 locus for autosomal dominant retinitis pigmentosa on 7q: refined genetic positioning and localization within a well-defined YAC contig.},
volume = {6}, 
number = {4}, 
pages = {255-266}, 
year = {1996}, 
doi = {10.1101/gr.6.4.255}, 
abstract ={Retinitis pigmentosa is a genetically heterogeneous disease that has autosomal dominant, autosomal recessive and X-linked forms. Autosomal dominant retinitis pigmentosa (adRP) has thus far been associated with eight distinct loci, including the rhodopsin and peripherin/RDS genes as well as unidentified genes on chromosomes 7p, 7q, 8q, 17p, 17q, and 19q. The RP10 locus for adRP on chromosome 7q was first mapped in a Spanish family; later, an unrelated American family was identified that also showed linkage to 7q. By combining the linkage results from both families, we are able to assign the disease gene to a 5-cM interval on 7q. Based on extensive physical mapping of this region, the genetic interval is now fully contained within a approximately 5-Mb segment on a well-defined YAC contig. These studies significantly reduce the size of the RP10 critical region, exclude a number of possible candidate genes, and provide the necessary cloned DNA for the positional cloning of the RP10 gene.}, 
URL = {http://genome.cshlp.org/content/6/4/255.abstract}, 
eprint = {http://genome.cshlp.org/content/6/4/255.full.pdf+html}, 
journal = {Genome Research} 
}