TY - JOUR A1 - Taylor, K A1 - Hornigold, N A1 - Conway, D A1 - Williams, D A1 - Ulinowski, Z A1 - Agochiya, M A1 - Fattorini, P A1 - de Jong, P A1 - Little, P F A1 - Wolfe, J T1 - Mapping the human Y chromosome by fingerprinting cosmid clones. Y1 - 1996/04/01 JF - Genome Research JO - Genome Research SP - 235 EP - 248 DO - 10.1101/gr.6.4.235 VL - 6 IS - 4 UR - http://genome.cshlp.org/content/6/4/235.abstract N2 - We have used Y-specific cosmid clones in a random fingerprinting approach to build contigs on the human Y chromosome. Clones derived from two libraries have been analyzed. The construction of one library is described here, the second was the Y chromosome-specific library LLOYNCO3 "M" (Lawrence Livermore National Laboratory). To date, we have fingerprinted 4430 cosmids: 377 contigs have been constructed containing from 2 to 39 clones. Along with the singletons, we estimate that we have covered 72.5% of the euchomatic portion of the Y chromosome with fingerprinted clones. Sequence tagged sites are being used to anchor cosmids and contigs onto the YAC framework. ER -