RT Journal
A1 McDermid, H E
A1 McTaggart, K E
A1 Riazi, M A
A1 Hudson, T J
A1 Budarf, M L
A1 Emanuel, B S
A1 Bell, C J
T1 Long-range mapping and construction of a YAC contig within the cat eye syndrome critical region.
JF Genome Research 
JO Genome Research 
YR 1996 
FD December 01 
VO 6 
IS 12 
SP 1149 
OP 1159 
DO 10.1101/gr.6.12.1149 
UL http://genome.cshlp.org/content/6/12/1149.abstract 
AB Cat eye syndrome (CES) is typically associated with a supernumerary bisatellited marker chromosome derived from human chromosome 22pter to 22q11.2. The region of 22q duplicated in the typical CES marker chromosome extends between the centromere and locus D22S36. We have constructed a long-range restriction map of this region using pulsed-field gel electrophoresis and probes to 10 loci (11 probes). The map covers -3.6 Mb. We have also used 15 loci to construct a yeast artificial chromosome contig, which encompasses about half of the region critical to the production of the CES phenotype (centromere to D22S57). Thus, the CES critical region has been mapped and a substantial portion of it cloned in preparation for the isolation of genes in this region.