RT Journal
A1 McKinnon, P J
A1 Kapsetaki, M
A1 Margolskee, R F
T1 The exon structure of the mouse Sc1 gene is very similar to the mouse Sparc gene.
JF Genome Research 
JO Genome Research 
YR 1996 
FD November 01 
VO 6 
IS 11 
SP 1077 
OP 1083 
DO 10.1101/gr.6.11.1077 
UL http://genome.cshlp.org/content/6/11/1077.abstract 
AB Sc1 and Sparc are two extracellular proteins sharing similarity in their carboxyl terminus, with 63% identity over a 232-amino-acid region. We have cloned and mapped the genomic locus of mouse Sc1. The mouse Sc1 gene contains 11 exons spanning approximately 35 kb of DNA. The genomic structure (exon/intron boundaries) of Sc1 exons 6 to exon 11 is identical to those of the similar portion of the Sparc gene. This suggests that Sc1 and Sparc originated from a common ancestral gene. Using fluorescence in situ hybridization analysis, Sc1 was localized to band 5E4 of mouse chromosome 5.