RT Journal
A1 Feng, J
A1 Li, Y
A1 Hashad, M
A1 Schurr, E
A1 Gros, P
A1 Adams, L G
A1 Templeton, J W
T1 Bovine natural resistance associated macrophage protein 1 (Nramp1) gene.
JF Genome Research 
JO Genome Research 
YR 1996 
FD October 01 
VO 6 
IS 10 
SP 956 
OP 964 
DO 10.1101/gr.6.10.956 
UL http://genome.cshlp.org/content/6/10/956.abstract 
AB The Bcg/Ity/Lsh locus is a major gene controlling early phases of infection with intracellular parasites in mice. Natural resistance associated macrophage protein 1 (Nramp1) has been shown to be the Bcg gene in mice. Analysis of a bovine cDNA homolog of murine Nramp1, designated as bovine NRAMP1, predicted a 548-amino-acid protein with hydrophobic domains, an amino-terminal SH3-binding domain, and a conserved consensus transport motif. Northern blotting indicated that bovine NRAMP1 was expressed primarily in macrophages and tissues of the recticuloendothelial system. Bovine NRAMP1 was mapped to BTA 2 within syntenic loci conserved on HSA 2q and MMU 1.