RT Journal
A1 Loftus, S K
A1 Dixon, J
A1 Koprivnikar, K
A1 Dixon, M J
A1 Wasmuth, J J
T1 Transcriptional map of the Treacher Collins candidate gene region.
JF Genome Research 
JO Genome Research 
YR 1996 
FD January 01 
VO 6 
IS 1 
SP 26 
OP 34 
DO 10.1101/gr.6.1.26 
UL http://genome.cshlp.org/content/6/1/26.abstract 
AB Treacher Collins syndrome (TCOF1) is a dominant disorder of craniofacial development that has been linked previosuly to a region of chromosome 5q31.3-32. Identification of recombination events in affected individuals has reduced the candidate gene region to a 0.5-Mb area between the loci RPS14 (proximal) and ANX6 [distal]. A transcriptional map of this candidate gene region, generated by analysis of exon amplification clones, has identified the genomic location of four genes, heparan sulfate-N-sulfotransferase-N-deacetylase, glutathione peroxidase, as well as two novel, previously uncharacterized genes. Each of these genes, based on their location, must be considered candidates for TCOF1 locus.