TY  - JOUR
A1  - Munro, Rory
A1  - Payne, Alexander
A1  - Holmes, Nadine
A1  - Moore, Chris
A1  - Cahyani, Inswasti
A1  - Loose, Matthew
T1  - Enhancing nanopore adaptive sampling for PromethION using readfish at scale
Y1  - 2025/04/01 
JF  - Genome Research 
JO  - Genome Research 
SP  - 877 
EP  - 885 
DO  - 10.1101/gr.279329.124 
VL  - 35 
IS  - 4 
UR  - http://genome.cshlp.org/content/35/4/877.abstract 
N2  - A unique feature of Oxford Nanopore Technologies sequencers, adaptive sampling, allows precise DNA molecule selection from sequencing libraries. Here, we present enhancements to our tool, readfish, enabling all features for the industrial scale PromethION sequencer, including standard and “barcode-aware” adaptive sampling. We demonstrate effective coverage enrichment and assessment of multiple human genomes for copy number and structural variation on a single PromethION flow cell. 
ER  -