@article{Yu01082020, author = {Yu, Ting and Mu, Zengchao and Fang, Zhaoyuan and Liu, Xiaoping and Gao, Xin and Liu, Juntao}, title = {TransBorrow: genome-guided transcriptome assembly by borrowing assemblies from different assemblers}, volume = {30}, number = {8}, pages = {1181-1190}, year = {2020}, doi = {10.1101/gr.257766.119}, abstract ={RNA-seq technology is widely used in various transcriptomic studies and provides great opportunities to reveal the complex structures of transcriptomes. To effectively analyze RNA-seq data, we introduce a novel transcriptome assembler, TransBorrow, which borrows the assemblies from different assemblers to search for reliable subsequences by building a colored graph from those borrowed assemblies. Then, by seeding reliable subsequences, a newly designed path extension strategy accurately searches for a transcript-representing path cover over each splicing graph. TransBorrow was tested on both simulated and real data sets and showed great superiority over all the compared leading assemblers.}, URL = {http://genome.cshlp.org/content/30/8/1181.abstract}, eprint = {http://genome.cshlp.org/content/30/8/1181.full.pdf+html}, journal = {Genome Research} }