TY  - JOUR
A1  - Ramilowski, Jordan A.
A1  - Yip, Chi Wai
A1  - Agrawal, Saumya
A1  - Chang, Jen-Chien
A1  - Ciani, Yari
A1  - Kulakovskiy, Ivan V.
A1  - Mendez, Mickaël
A1  - Ooi, Jasmine Li Ching
A1  - Ouyang, John F.
A1  - Parkinson, Nick
A1  - Petri, Andreas
A1  - Roos, Leonie
A1  - Severin, Jessica
A1  - Yasuzawa, Kayoko
A1  - Abugessaisa, Imad
A1  - Akalin, Altuna
A1  - Antonov, Ivan V.
A1  - Arner, Erik
A1  - Bonetti, Alessandro
A1  - Bono, Hidemasa
A1  - Borsari, Beatrice
A1  - Brombacher, Frank
A1  - Cameron, Christopher J.F.
A1  - Cannistraci, Carlo Vittorio
A1  - Cardenas, Ryan
A1  - Cardon, Melissa
A1  - Chang, Howard
A1  - Dostie, Josée
A1  - Ducoli, Luca
A1  - Favorov, Alexander
A1  - Fort, Alexandre
A1  - Garrido, Diego
A1  - Gil, Noa
A1  - Gimenez, Juliette
A1  - Guler, Reto
A1  - Handoko, Lusy
A1  - Harshbarger, Jayson
A1  - Hasegawa, Akira
A1  - Hasegawa, Yuki
A1  - Hashimoto, Kosuke
A1  - Hayatsu, Norihito
A1  - Heutink, Peter
A1  - Hirose, Tetsuro
A1  - Imada, Eddie L.
A1  - Itoh, Masayoshi
A1  - Kaczkowski, Bogumil
A1  - Kanhere, Aditi
A1  - Kawabata, Emily
A1  - Kawaji, Hideya
A1  - Kawashima, Tsugumi
A1  - Kelly, S. Thomas
A1  - Kojima, Miki
A1  - Kondo, Naoto
A1  - Koseki, Haruhiko
A1  - Kouno, Tsukasa
A1  - Kratz, Anton
A1  - Kurowska-Stolarska, Mariola
A1  - Kwon, Andrew Tae Jun
A1  - Leek, Jeffrey
A1  - Lennartsson, Andreas
A1  - Lizio, Marina
A1  - López-Redondo, Fernando
A1  - Luginbühl, Joachim
A1  - Maeda, Shiori
A1  - Makeev, Vsevolod J.
A1  - Marchionni, Luigi
A1  - Medvedeva, Yulia A.
A1  - Minoda, Aki
A1  - Müller, Ferenc
A1  - Muñoz-Aguirre, Manuel
A1  - Murata, Mitsuyoshi
A1  - Nishiyori, Hiromi
A1  - Nitta, Kazuhiro R.
A1  - Noguchi, Shuhei
A1  - Noro, Yukihiko
A1  - Nurtdinov, Ramil
A1  - Okazaki, Yasushi
A1  - Orlando, Valerio
A1  - Paquette, Denis
A1  - Parr, Callum J.C.
A1  - Rackham, Owen J.L.
A1  - Rizzu, Patrizia
A1  - Sánchez Martinez, Diego Fernando
A1  - Sandelin, Albin
A1  - Sanjana, Pillay
A1  - Semple, Colin A.M.
A1  - Shibayama, Youtaro
A1  - Sivaraman, Divya M.
A1  - Suzuki, Takahiro
A1  - Szumowski, Suzannah C.
A1  - Tagami, Michihira
A1  - Taylor, Martin S.
A1  - Terao, Chikashi
A1  - Thodberg, Malte
A1  - Thongjuea, Supat
A1  - Tripathi, Vidisha
A1  - Ulitsky, Igor
A1  - Verardo, Roberto
A1  - Vorontsov, Ilya E.
A1  - Yamamoto, Chinatsu
A1  - Young, Robert S.
A1  - Baillie, J. Kenneth
A1  - Forrest, Alistair R.R.
A1  - Guigó, Roderic
A1  - Hoffman, Michael M.
A1  - Hon, Chung Chau
A1  - Kasukawa, Takeya
A1  - Kauppinen, Sakari
A1  - Kere, Juha
A1  - Lenhard, Boris
A1  - Schneider, Claudio
A1  - Suzuki, Harukazu
A1  - Yagi, Ken
A1  - de Hoon, Michiel J.L.
A1  - Shin, Jay W.
A1  - Carninci, Piero
T1  - Functional annotation of human long noncoding RNAs via molecular phenotyping
Y1  - 2020/07/01 
JF  - Genome Research 
JO  - Genome Research 
SP  - 1060 
EP  - 1072 
DO  - 10.1101/gr.254219.119 
VL  - 30 
IS  - 7 
UR  - http://genome.cshlp.org/content/30/7/1060.abstract 
N2  - Long noncoding RNAs (lncRNAs) constitute the majority of transcripts in the mammalian genomes, and yet, their functions remain largely unknown. As part of the FANTOM6 project, we systematically knocked down the expression of 285 lncRNAs in human dermal fibroblasts and quantified cellular growth, morphological changes, and transcriptomic responses using Capped Analysis of Gene Expression (CAGE). Antisense oligonucleotides targeting the same lncRNAs exhibited global concordance, and the molecular phenotype, measured by CAGE, recapitulated the observed cellular phenotypes while providing additional insights on the affected genes and pathways. Here, we disseminate the largest-to-date lncRNA knockdown data set with molecular phenotyping (over 1000 CAGE deep-sequencing libraries) for further exploration and highlight functional roles for ZNF213-AS1 and lnc-KHDC3L-2. 
ER  -