RT Journal
A1 Zhou, Zhemin
A1 Alikhan, Nabil-Fareed
A1 Sergeant, Martin J.
A1 Luhmann, Nina
A1 Vaz, Cátia
A1 Francisco, Alexandre P.
A1 Carriço, João André
A1 Achtman, Mark
T1 GrapeTree: visualization of core genomic relationships among 100,000 bacterial pathogens
JF Genome Research 
JO Genome Research 
YR 2018 
FD September 01 
VO 28 
IS 9 
SP 1395 
OP 1404 
DO 10.1101/gr.232397.117 
UL http://genome.cshlp.org/content/28/9/1395.abstract 
AB Current methods struggle to reconstruct and visualize the genomic relationships of large numbers of bacterial genomes. GrapeTree facilitates the analyses of large numbers of allelic profiles by a static “GrapeTree Layout” algorithm that supports interactive visualizations of large trees within a web browser window. GrapeTree also implements a novel minimum spanning tree algorithm (MSTree V2) to reconstruct genetic relationships despite high levels of missing data. GrapeTree is a stand-alone package for investigating phylogenetic trees plus associated metadata and is also integrated into EnteroBase to facilitate cutting edge navigation of genomic relationships among bacterial pathogens.