TY  - JOUR
A1  - Zhou, Zhemin
A1  - Alikhan, Nabil-Fareed
A1  - Sergeant, Martin J.
A1  - Luhmann, Nina
A1  - Vaz, Cátia
A1  - Francisco, Alexandre P.
A1  - Carriço, João André
A1  - Achtman, Mark
T1  - GrapeTree: visualization of core genomic relationships among 100,000 bacterial pathogens
Y1  - 2018/09/01 
JF  - Genome Research 
JO  - Genome Research 
SP  - 1395 
EP  - 1404 
DO  - 10.1101/gr.232397.117 
VL  - 28 
IS  - 9 
UR  - http://genome.cshlp.org/content/28/9/1395.abstract 
N2  - Current methods struggle to reconstruct and visualize the genomic relationships of large numbers of bacterial genomes. GrapeTree facilitates the analyses of large numbers of allelic profiles by a static “GrapeTree Layout” algorithm that supports interactive visualizations of large trees within a web browser window. GrapeTree also implements a novel minimum spanning tree algorithm (MSTree V2) to reconstruct genetic relationships despite high levels of missing data. GrapeTree is a stand-alone package for investigating phylogenetic trees plus associated metadata and is also integrated into EnteroBase to facilitate cutting edge navigation of genomic relationships among bacterial pathogens. 
ER  -