@article{Zhou01092018, author = {Zhou, Zhemin and Alikhan, Nabil-Fareed and Sergeant, Martin J. and Luhmann, Nina and Vaz, Cátia and Francisco, Alexandre P. and Carriço, João André and Achtman, Mark}, title = {GrapeTree: visualization of core genomic relationships among 100,000 bacterial pathogens}, volume = {28}, number = {9}, pages = {1395-1404}, year = {2018}, doi = {10.1101/gr.232397.117}, abstract ={Current methods struggle to reconstruct and visualize the genomic relationships of large numbers of bacterial genomes. GrapeTree facilitates the analyses of large numbers of allelic profiles by a static “GrapeTree Layout” algorithm that supports interactive visualizations of large trees within a web browser window. GrapeTree also implements a novel minimum spanning tree algorithm (MSTree V2) to reconstruct genetic relationships despite high levels of missing data. GrapeTree is a stand-alone package for investigating phylogenetic trees plus associated metadata and is also integrated into EnteroBase to facilitate cutting edge navigation of genomic relationships among bacterial pathogens.}, URL = {http://genome.cshlp.org/content/28/9/1395.abstract}, eprint = {http://genome.cshlp.org/content/28/9/1395.full.pdf+html}, journal = {Genome Research} }