TY  - JOUR
A1  - Gardiner, Laura-Jayne
A1  - Joynson, Ryan
A1  - Omony, Jimmy
A1  - Rusholme-Pilcher, Rachel
A1  - Olohan, Lisa
A1  - Lang, Daniel
A1  - Bai, Caihong
A1  - Hawkesford, Malcolm
A1  - Salt, David
A1  - Spannagl, Manuel
A1  - Mayer, Klaus F.X.
A1  - Kenny, John
A1  - Bevan, Michael
A1  - Hall, Neil
A1  - Hall, Anthony
T1  - Hidden variation in polyploid wheat drives local adaptation
Y1  - 2018/09/01 
JF  - Genome Research 
JO  - Genome Research 
SP  - 1319 
EP  - 1332 
DO  - 10.1101/gr.233551.117 
VL  - 28 
IS  - 9 
UR  - http://genome.cshlp.org/content/28/9/1319.abstract 
N2  - Wheat has been domesticated into a large number of agricultural environments and has the ability to adapt to diverse environments. To understand this process, we survey genotype, repeat content, and DNA methylation across a bread wheat landrace collection representing global genetic diversity. We identify independent variation in methylation, genotype, and transposon copy number. We show that these, so far unexploited, sources of variation have had a significant impact on the wheat genome and that ancestral methylation states become preferentially “hard coded” as single nucleotide polymorphisms (SNPs) via 5-methylcytosine deamination. These mechanisms also drive local adaption, impacting important traits such as heading date and salt tolerance. Methylation and transposon diversity could therefore be used alongside SNP-based markers for breeding. 
ER  -