TY - JOUR A1 - Nurk, Sergey A1 - Meleshko, Dmitry A1 - Korobeynikov, Anton A1 - Pevzner, Pavel A. T1 - metaSPAdes: a new versatile metagenomic assembler Y1 - 2017/05/01 JF - Genome Research JO - Genome Research SP - 824 EP - 834 DO - 10.1101/gr.213959.116 VL - 27 IS - 5 UR - http://genome.cshlp.org/content/27/5/824.abstract N2 - While metagenomics has emerged as a technology of choice for analyzing bacterial populations, the assembly of metagenomic data remains challenging, thus stifling biological discoveries. Moreover, recent studies revealed that complex bacterial populations may be composed from dozens of related strains, thus further amplifying the challenge of metagenomic assembly. metaSPAdes addresses various challenges of metagenomic assembly by capitalizing on computational ideas that proved to be useful in assemblies of single cells and highly polymorphic diploid genomes. We benchmark metaSPAdes against other state-of-the-art metagenome assemblers and demonstrate that it results in high-quality assemblies across diverse data sets. ER -