TY  - JOUR
A1  - Vaser, Robert
A1  - Sović, Ivan
A1  - Nagarajan, Niranjan
A1  - Šikić, Mile
T1  - Fast and accurate de novo genome assembly from long uncorrected reads
Y1  - 2017/05/01 
JF  - Genome Research 
JO  - Genome Research 
SP  - 737 
EP  - 746 
DO  - 10.1101/gr.214270.116 
VL  - 27 
IS  - 5 
UR  - http://genome.cshlp.org/content/27/5/737.abstract 
N2  - The assembly of long reads from Pacific Biosciences and Oxford Nanopore Technologies typically requires resource-intensive error-correction and consensus-generation steps to obtain high-quality assemblies. We show that the error-correction step can be omitted and that high-quality consensus sequences can be generated efficiently with a SIMD-accelerated, partial-order alignment–based, stand-alone consensus module called Racon. Based on tests with PacBio and Oxford Nanopore data sets, we show that Racon coupled with miniasm enables consensus genomes with similar or better quality than state-of-the-art methods while being an order of magnitude faster. 
ER  -