TY  - JOUR
A1  - Skinner, Benjamin M.
A1  - Sargent, Carole A.
A1  - Churcher, Carol
A1  - Hunt, Toby
A1  - Herrero, Javier
A1  - Loveland, Jane E.
A1  - Dunn, Matt
A1  - Louzada, Sandra
A1  - Fu, Beiyuan
A1  - Chow, William
A1  - Gilbert, James
A1  - Austin-Guest, Siobhan
A1  - Beal, Kathryn
A1  - Carvalho-Silva, Denise
A1  - Cheng, William
A1  - Gordon, Daria
A1  - Grafham, Darren
A1  - Hardy, Matt
A1  - Harley, Jo
A1  - Hauser, Heidi
A1  - Howden, Philip
A1  - Howe, Kerstin
A1  - Lachani, Kim
A1  - Ellis, Peter J.I.
A1  - Kelly, Daniel
A1  - Kerry, Giselle
A1  - Kerwin, James
A1  - Ng, Bee Ling
A1  - Threadgold, Glen
A1  - Wileman, Thomas
A1  - Wood, Jonathan M.D.
A1  - Yang, Fengtang
A1  - Harrow, Jen
A1  - Affara, Nabeel A.
A1  - Tyler-Smith, Chris
T1  - The pig X and Y Chromosomes: structure, sequence, and evolution
Y1  - 2016/01/01 
JF  - Genome Research 
JO  - Genome Research 
SP  - 130 
EP  - 139 
DO  - 10.1101/gr.188839.114 
VL  - 26 
IS  - 1 
UR  - http://genome.cshlp.org/content/26/1/130.abstract 
N2  - We have generated an improved assembly and gene annotation of the pig X Chromosome, and a first draft assembly of the pig Y Chromosome, by sequencing BAC and fosmid clones from Duroc animals and incorporating information from optical mapping and fiber-FISH. The X Chromosome carries 1033 annotated genes, 690 of which are protein coding. Gene order closely matches that found in primates (including humans) and carnivores (including cats and dogs), which is inferred to be ancestral. Nevertheless, several protein-coding genes present on the human X Chromosome were absent from the pig, and 38 pig-specific X-chromosomal genes were annotated, 22 of which were olfactory receptors. The pig Y-specific Chromosome sequence generated here comprises 30 megabases (Mb). A 15-Mb subset of this sequence was assembled, revealing two clusters of male-specific low copy number genes, separated by an ampliconic region including the HSFY gene family, which together make up most of the short arm. Both clusters contain palindromes with high sequence identity, presumably maintained by gene conversion. Many of the ancestral X-related genes previously reported in at least one mammalian Y Chromosome are represented either as active genes or partial sequences. This sequencing project has allowed us to identify genes—both single copy and amplified—on the pig Y Chromosome, to compare the pig X and Y Chromosomes for homologous sequences, and thereby to reveal mechanisms underlying pig X and Y Chromosome evolution. 
ER  -