TY  - JOUR
A1  - Wheeler, David A.
A1  - Wang, Linghua
T1  - From human genome to cancer genome: The first decade
Y1  - 2013/07/01 
JF  - Genome Research 
JO  - Genome Research 
SP  - 1054 
EP  - 1062 
DO  - 10.1101/gr.157602.113 
VL  - 23 
IS  - 7 
UR  - http://genome.cshlp.org/content/23/7/1054.abstract 
N2  - The realization that cancer progression required the participation of cellular genes provided one of several key rationales, in 1986, for embarking on the human genome project. Only with a reference genome sequence could the full spectrum of somatic changes leading to cancer be understood. Since its completion in 2003, the human reference genome sequence has fulfilled its promise as a foundational tool to illuminate the pathogenesis of cancer. Herein, we review the key historical milestones in cancer genomics since the completion of the genome, and some of the novel discoveries that are shaping our current understanding of cancer. 
ER  -