TY  - JOUR
A1  - Schmitz, Robert J.
A1  - He, Yupeng
A1  - Valdés-López, Oswaldo
A1  - Khan, Saad M.
A1  - Joshi, Trupti
A1  - Urich, Mark A.
A1  - Nery, Joseph R.
A1  - Diers, Brian
A1  - Xu, Dong
A1  - Stacey, Gary
A1  - Ecker, Joseph R.
T1  - Epigenome-wide inheritance of cytosine methylation variants in a recombinant inbred population
Y1  - 2013/10/01 
JF  - Genome Research 
JO  - Genome Research 
SP  - 1663 
EP  - 1674 
DO  - 10.1101/gr.152538.112 
VL  - 23 
IS  - 10 
UR  - http://genome.cshlp.org/content/23/10/1663.abstract 
N2  - Cytosine DNA methylation is one avenue for passing information through cell divisions. Here, we present epigenomic analyses of soybean recombinant inbred lines (RILs) and their parents. Identification of differentially methylated regions (DMRs) revealed that DMRs mostly cosegregated with the genotype from which they were derived, but examples of the uncoupling of genotype and epigenotype were identified. Linkage mapping of methylation states assessed from whole-genome bisulfite sequencing of 83 RILs uncovered widespread evidence for local methylQTL. This epigenomics approach provides a comprehensive study of the patterns and heritability of methylation variants in a complex genetic population over multiple generations, paving the way for understanding how methylation variants contribute to phenotypic variation. 
ER  -