TY - JOUR A1 - Vucic, Emily A. A1 - Thu, Kelsie L. A1 - Robison, Keith A1 - Rybaczyk, Leszek A. A1 - Chari, Raj A1 - Alvarez, Carlos E. A1 - Lam, Wan L. T1 - Translating cancer ‘omics’ to improved outcomes Y1 - 2012/02/01 JF - Genome Research JO - Genome Research SP - 188 EP - 195 DO - 10.1101/gr.124354.111 VL - 22 IS - 2 UR - http://genome.cshlp.org/content/22/2/188.abstract N2 - The genomics era has yielded great advances in the understanding of cancer biology. At the same time, the immense complexity of the cancer genome has been revealed, as well as a striking heterogeneity at the whole-genome (or omics) level that exists between even histologically similar tumors. The vast accrual and public availability of multi-omics databases with associated clinical annotation including tumor histology, patient response, and outcome are a rich resource that has the potential to lead to rapid translation of high-throughput omics to improved overall survival. We focus on the unique advantages of a multidimensional approach to genomic analysis in this new high-throughput omics age and discuss the implications of the changing cancer demographic to translational omics research. ER -