TY  - JOUR
A1  - Krzywinski, Martin
A1  - Schein, Jacqueline
A1  - Birol, İnanç
A1  - Connors, Joseph
A1  - Gascoyne, Randy
A1  - Horsman, Doug
A1  - Jones, Steven J.
A1  - Marra, Marco A.
T1  - Circos: An information aesthetic for comparative genomics
Y1  - 2009/09/01 
JF  - Genome Research 
JO  - Genome Research 
SP  - 1639 
EP  - 1645 
DO  - 10.1101/gr.092759.109 
VL  - 19 
IS  - 9 
UR  - http://genome.cshlp.org/content/19/9/1639.abstract 
N2  - We created a visualization tool called Circos to facilitate the identification and analysis of similarities and differences arising from comparisons of genomes. Our tool is effective in displaying variation in genome structure and, generally, any other kind of positional relationships between genomic intervals. Such data are routinely produced by sequence alignments, hybridization arrays, genome mapping, and genotyping studies. Circos uses a circular ideogram layout to facilitate the display of relationships between pairs of positions by the use of ribbons, which encode the position, size, and orientation of related genomic elements. Circos is capable of displaying data as scatter, line, and histogram plots, heat maps, tiles, connectors, and text. Bitmap or vector images can be created from GFF-style data inputs and hierarchical configuration files, which can be easily generated by automated tools, making Circos suitable for rapid deployment in data analysis and reporting pipelines. 
ER  -