TY  - JOUR
A1  - The Génolevures Consortium
A1  - Souciet, Jean-Luc
A1  - Dujon, Bernard
A1  - Gaillardin, Claude
A1  - Johnston, Mark
A1  - Baret, Philippe V.
A1  - Cliften, Paul
A1  - Sherman, David J.
A1  - Weissenbach, Jean
A1  - Westhof, Eric
A1  - Wincker, Patrick
A1  - Jubin, Claire
A1  - Poulain, Julie
A1  - Barbe, Valérie
A1  - Ségurens, Béatrice
A1  - Artiguenave, François
A1  - Anthouard, Véronique
A1  - Vacherie, Benoit
A1  - Val, Marie-Eve
A1  - Fulton, Robert S.
A1  - Minx, Patrick
A1  - Wilson, Richard
A1  - Durrens, Pascal
A1  - Jean, Géraldine
A1  - Marck, Christian
A1  - Martin, Tiphaine
A1  - Nikolski, Macha
A1  - Rolland, Thomas
A1  - Seret, Marie-Line
A1  - Casarégola, Serge
A1  - Despons, Laurence
A1  - Fairhead, Cécile
A1  - Fischer, Gilles
A1  - Lafontaine, Ingrid
A1  - Leh, Véronique
A1  - Lemaire, Marc
A1  - de Montigny, Jacky
A1  - Neuvéglise, Cécile
A1  - Thierry, Agnès
A1  - Blanc-Lenfle, Isabelle
A1  - Bleykasten, Claudine
A1  - Diffels, Julie
A1  - Fritsch, Emilie
A1  - Frangeul, Lionel
A1  - Goëffon, Adrien
A1  - Jauniaux, Nicolas
A1  - Kachouri-Lafond, Rym
A1  - Payen, Célia
A1  - Potier, Serge
A1  - Pribylova, Lenka
A1  - Ozanne, Christophe
A1  - Richard, Guy-Franck
A1  - Sacerdot, Christine
A1  - Straub, Marie-Laure
A1  - Talla, Emmanuel
T1  - Comparative genomics of protoploid Saccharomycetaceae
Y1  - 2009/10/01 
JF  - Genome Research 
JO  - Genome Research 
SP  - 1696 
EP  - 1709 
DO  - 10.1101/gr.091546.109 
VL  - 19 
IS  - 10 
UR  - http://genome.cshlp.org/content/19/10/1696.abstract 
N2  - Our knowledge of yeast genomes remains largely dominated by the extensive studies on Saccharomyces cerevisiae and the consequences of its ancestral duplication, leaving the evolution of the entire class of hemiascomycetes only partly explored. We concentrate here on five species of Saccharomycetaceae, a large subdivision of hemiascomycetes, that we call “protoploid” because they diverged from the S. cerevisiae lineage prior to its genome duplication. We determined the complete genome sequences of three of these species: Kluyveromyces (Lachancea) thermotolerans and Saccharomyces (Lachancea) kluyveri (two members of the newly described Lachancea clade), and Zygosaccharomyces rouxii. We included in our comparisons the previously available sequences of Kluyveromyces lactis and Ashbya (Eremothecium) gossypii. Despite their broad evolutionary range and significant individual variations in each lineage, the five protoploid Saccharomycetaceae share a core repertoire of approximately 3300 protein families and a high degree of conserved synteny. Synteny blocks were used to define gene orthology and to infer ancestors. Far from representing minimal genomes without redundancy, the five protoploid yeasts contain numerous copies of paralogous genes, either dispersed or in tandem arrays, that, altogether, constitute a third of each genome. Ancient, conserved paralogs as well as novel, lineage-specific paralogs were identified. 
ER  -