RT Journal
A1 L. Strausberg, Robert
A1 Levy, Samuel
T1 Promoting transcriptome diversity
JF Genome Research 
JO Genome Research 
YR 2007 
FD July 01 
VO 17 
IS 7 
SP 965 
OP 968 
DO 10.1101/gr.6499807 
UL http://genome.cshlp.org/content/17/7/965.abstract 
AB Although the number of protein-encoding human genes is more limited than many had estimated, the human transcript repertoire is much more diverse than anticipated. In part, transcript diversity is generated through the use of alternative promoters and alternate splicing. In addition, based on discoveries using technologies such as full-length cDNA libraries and whole genome tiling microarrays, it is now likely that non-protein-encoding transcripts comprise a substantial fraction of the human RNA population. Much attention is currently focused on understanding the role of alternative promoters in generating transcript diversity, both for non-protein-encoding (ncRNAs) and protein-encoding RNAs.