@article{Bollenbach01042007,
author = {Bollenbach, Tobias and Vetsigian, Kalin and Kishony, Roy}, 
title = {Evolution and multilevel optimization of the genetic code},
volume = {17}, 
number = {4}, 
pages = {401-404}, 
year = {2007}, 
doi = {10.1101/gr.6144007}, 
abstract ={The discovery of the genetic code was one of the most important advances of modern biology. But there is more to a DNA code than protein sequence; DNA carries signals for splicing, localization, folding, and regulation that are often embedded within the protein-coding sequence. In this issue, Itzkovitz and Alon show that the specific 64-to-20 mapping found in the genetic code may have been optimized for permitting protein-coding regions to carry this extra information and suggest that this property may have evolved as a side benefit of selection to minimize the negative effects of frameshift errors.}, 
URL = {http://genome.cshlp.org/content/17/4/401.abstract}, 
eprint = {http://genome.cshlp.org/content/17/4/401.full.pdf+html}, 
journal = {Genome Research} 
}