TY  - JOUR
A1  - Ling, King-Hwa
A1  - Rajandream, Marie-Adele
A1  - Rivailler, Pierre
A1  - Ivens, Alasdair
A1  - Yap, Soon-Joo
A1  - Madeira, Alda M.B.N.
A1  - Mungall, Karen
A1  - Billington, Karen
A1  - Yee, Wai-Yan
A1  - Bankier, Alan T.
A1  - Carroll, Fionnadh
A1  - Durham, Alan M.
A1  - Peters, Nicholas
A1  - Loo, Shu-San
A1  - Mat Isa, Mohd Noor
A1  - Novaes, Jeniffer
A1  - Quail, Michael
A1  - Rosli, Rozita
A1  - Nor Shamsudin, Mariana
A1  - Sobreira, Tiago J.P.
A1  - Tivey, Adrian R.
A1  - Wai, Siew-Fun
A1  - White, Sarah
A1  - Wu, Xikun
A1  - Kerhornou, Arnaud
A1  - Blake, Damer
A1  - Mohamed, Rahmah
A1  - Shirley, Martin
A1  - Gruber, Arthur
A1  - Berriman, Matthew
A1  - Tomley, Fiona
A1  - Dear, Paul H.
A1  - Wan, Kiew-Lian
T1  - Sequencing and analysis of chromosome 1 of Eimeria tenella reveals a unique segmental organization
Y1  - 2007/03/01 
JF  - Genome Research 
JO  - Genome Research 
SP  - 311 
EP  - 319 
DO  - 10.1101/gr.5823007 
VL  - 17 
IS  - 3 
UR  - http://genome.cshlp.org/content/17/3/311.abstract 
N2  - Eimeria tenella is an intracellular protozoan parasite that infects the intestinal tracts of domestic fowl and causes coccidiosis, a serious and sometimes lethal enteritis. Eimeria falls in the same phylum (Apicomplexa) as several human and animal parasites such as Cryptosporidium, Toxoplasma, and the malaria parasite, Plasmodium. Here we report the sequencing and analysis of the first chromosome of E. tenella, a chromosome believed to carry loci associated with drug resistance and known to differ between virulent and attenuated strains of the parasite. The chromosome—which appears to be representative of the genome—is gene-dense and rich in simple-sequence repeats, many of which appear to give rise to repetitive amino acid tracts in the predicted proteins. Most striking is the segmentation of the chromosome into repeat-rich regions peppered with transposon-like elements and telomere-like repeats, alternating with repeat-free regions. Predicted genes differ in character between the two types of segment, and the repeat-rich regions appear to be associated with strain-to-strain variation. 
ER  -