RT Journal A1 Goios, Ana A1 Pereira, Luísa A1 Bogue, Molly A1 Macaulay, Vincent A1 Amorim, António T1 mtDNA phylogeny and evolution of laboratory mouse strains JF Genome Research JO Genome Research YR 2007 FD March 01 VO 17 IS 3 SP 293 OP 298 DO 10.1101/gr.5941007 UL http://genome.cshlp.org/content/17/3/293.abstract AB Inbred mouse strains have been maintained for more than 100 years, and they are thought to be a mixture of four different mouse subspecies. Although genealogies have been established, female inbred mouse phylogenies remain unexplored. By a phylogenetic analysis of newly generated complete mitochondrial DNA sequence data in 16 strains, we show here that all common inbred strains descend from the same Mus musculus domesticus female wild ancestor, and suggest that they present a different mitochondrial evolutionary process than their wild relatives with a faster accumulation of replacement substitutions. Our data complement forthcoming results on resequencing of a group of priority strains, and they follow recent efforts of the Mouse Phenome Project to collect and make publicly available information on various strains.