@article{Pontius01112007,
author = {Pontius, Joan U. and Mullikin, James C. and Smith, Douglas R. and Agencourt Sequencing Team and Lindblad-Toh, Kerstin and Gnerre, Sante and Clamp, Michele and Chang, Jean and Stephens, Robert and Neelam, Beena and Volfovsky, Natalia and Schäffer, Alejandro A. and Agarwala, Richa and Narfström, Kristina and Murphy, William J. and Giger, Urs and Roca, Alfred L. and Antunes, Agostinho and Menotti-Raymond, Marilyn and Yuhki, Naoya and Pecon-Slattery, Jill and Johnson, Warren E. and Bourque, Guillaume and Tesler, Glenn and NISC Comparative Sequencing Program and O’Brien, Stephen J.}, 
title = {Initial sequence and comparative analysis of the cat genome},
volume = {17}, 
number = {11}, 
pages = {1675-1689}, 
year = {2007}, 
doi = {10.1101/gr.6380007}, 
abstract ={The genome sequence (1.9-fold coverage) of an inbred Abyssinian domestic cat was assembled, mapped, and annotated with a comparative approach that involved cross-reference to annotated genome assemblies of six mammals (human, chimpanzee, mouse, rat, dog, and cow). The results resolved chromosomal positions for 663,480 contigs, 20,285 putative feline gene orthologs, and 133,499 conserved sequence blocks (CSBs). Additional annotated features include repetitive elements, endogenous retroviral sequences, nuclear mitochondrial (numt) sequences, micro-RNAs, and evolutionary breakpoints that suggest historic balancing of translocation and inversion incidences in distinct mammalian lineages. Large numbers of single nucleotide polymorphisms (SNPs), deletion insertion polymorphisms (DIPs), and short tandem repeats (STRs), suitable for linkage or association studies were characterized in the context of long stretches of chromosome homozygosity. In spite of the light coverage capturing ∼65% of euchromatin sequence from the cat genome, these comparative insights shed new light on the tempo and mode of gene/genome evolution in mammals, promise several research applications for the cat, and also illustrate that a comparative approach using more deeply covered mammals provides an informative, preliminary annotation of a light (1.9-fold) coverage mammal genome sequence.}, 
URL = {http://genome.cshlp.org/content/17/11/1675.abstract}, 
eprint = {http://genome.cshlp.org/content/17/11/1675.full.pdf+html}, 
journal = {Genome Research} 
}