RT Journal
A1 Flaherty, Lorraine
A1 Herron, Bruce
A1 Symula, Derek
T1 Genomics of the future: Identification of quantitative trait loci in the mouse
JF Genome Research 
JO Genome Research 
YR 2005 
FD December 01 
VO 15 
IS 12 
SP 1741 
OP 1745 
DO 10.1101/gr.3841405 
UL http://genome.cshlp.org/content/15/12/1741.abstract 
AB Positional cloning of quantitative trait loci in rodents is a common approach to identify genes involved in complex phenotypes, including genes important to human disease. However, cloning the causative genes has proved to be more difficult than determining their positions. New tools such as genomic sequence, clone libraries, and new genomic-based methods offer new approaches to identify these genes. Here we review how these new tools and approaches will improve our ability to discover the genes important in complex traits.