TY - JOUR A1 - Flaherty, Lorraine A1 - Herron, Bruce A1 - Symula, Derek T1 - Genomics of the future: Identification of quantitative trait loci in the mouse Y1 - 2005/12/01 JF - Genome Research JO - Genome Research SP - 1741 EP - 1745 DO - 10.1101/gr.3841405 VL - 15 IS - 12 UR - http://genome.cshlp.org/content/15/12/1741.abstract N2 - Positional cloning of quantitative trait loci in rodents is a common approach to identify genes involved in complex phenotypes, including genes important to human disease. However, cloning the causative genes has proved to be more difficult than determining their positions. New tools such as genomic sequence, clone libraries, and new genomic-based methods offer new approaches to identify these genes. Here we review how these new tools and approaches will improve our ability to discover the genes important in complex traits. ER -