RT Journal
A1 Fraser-Liggett, Claire M.
T1 Insights on biology and evolution from microbial genome sequencing
JF Genome Research 
JO Genome Research 
YR 2005 
FD December 01 
VO 15 
IS 12 
SP 1603 
OP 1610 
DO 10.1101/gr.3724205 
UL http://genome.cshlp.org/content/15/12/1603.abstract 
AB No field of research has embraced and applied genomic technology more than the field of microbiology. Comparative analysis of nearly 300 microbial species has demonstrated that the microbial genome is a dynamic entity shaped by multiple forces. Microbial genomics has provided a foundation for a broad range of applications, from understanding basic biological processes, host-pathogen interactions, and protein-protein interactions, to discovering DNA variations that can be used in genotyping or forensic analyses, the design of novel antimicrobial compounds and vaccines, and the engineering of microbes for industrial applications. Most recently, metagenomics approaches are allowing us to begin to probe complex microbial communities for the first time, and they hold great promise in helping to unravel the relationships between microbial species.