TY - JOUR A1 - Giardine, Belinda A1 - Riemer, Cathy A1 - Hardison, Ross C. A1 - Burhans, Richard A1 - Elnitski, Laura A1 - Shah, Prachi A1 - Zhang, Yi A1 - Blankenberg, Daniel A1 - Albert, Istvan A1 - Taylor, James A1 - Miller, Webb A1 - Kent, W. James A1 - Nekrutenko, Anton T1 - Galaxy: A platform for interactive large-scale genome analysis Y1 - 2005/10/01 JF - Genome Research JO - Genome Research SP - 1451 EP - 1455 DO - 10.1101/gr.4086505 VL - 15 IS - 10 UR - http://genome.cshlp.org/content/15/10/1451.abstract N2 - Accessing and analyzing the exponentially expanding genomic sequence and functional data pose a challenge for biomedical researchers. Here we describe an interactive system, Galaxy, that combines the power of existing genome annotation databases with a simple Web portal to enable users to search remote resources, combine data from independent queries, and visualize the results. The heart of Galaxy is a flexible history system that stores the queries from each user; performs operations such as intersections, unions, and subtractions; and links to other computational tools. Galaxy can be accessed at http://g2.bx.psu.edu. ER -