TY  - JOUR
A1  - Westberg, Joakim
A1  - Persson, Anja
A1  - Holmberg, Anders
A1  - Goesmann, Alexander
A1  - Lundeberg, Joakim
A1  - Johansson, Karl-Erik
A1  - Pettersson, Bertil
A1  - Uhlén, Mathias
T1  - The Genome Sequence of Mycoplasma mycoides subsp. mycoides SC Type Strain PG1T, the Causative Agent of Contagious Bovine Pleuropneumonia (CBPP)
Y1  - 2004/02/01 
JF  - Genome Research 
JO  - Genome Research 
SP  - 221 
EP  - 227 
DO  - 10.1101/gr.1673304 
VL  - 14 
IS  - 2 
UR  - http://genome.cshlp.org/content/14/2/221.abstract 
N2  - Mycoplasma mycoides subsp. mycoidesSC (MmymySC)is the etiological agent of contagious bovine pleuropneumonia (CBPP), a highly contagious respiratory disease in cattle. The genome of Mmymy SC type strain PG1T has been sequenced to map all the genes and to facilitate further studies regarding the cell function of the organism and CBPP. The genome is characterized by a single circular chromosome of 1,211,703 bp with the lowest G+C content (24 mole%)and the highest density of insertion sequences (13% of the genome size)of all sequenced bacterial genomes. The genome contains 985 putative genes, of which 72 are part of insertion sequences and encode transposases. Anomalies in the GC-skew pattern and the presence of large repetitive sequences indicate a high genomic plasticity. A variety of potential virulence factors was identified, including genes encoding putative variable surface proteins and enzymes and transport proteins responsible for the production of hydrogen peroxide and the capsule, which is believed to have toxic effects on the animal. 
ER  -