RT Journal
A1 Le Roch, Karine G.
A1 Johnson, Jeffrey R.
A1 Florens, Laurence
A1 Zhou, Yingyao
A1 Santrosyan, Andrey
A1 Grainger, Munira
A1 Yan, S. Frank
A1 Williamson, Kim C.
A1 Holder, Anthony A.
A1 Carucci, Daniel J.
A1 Yates, John R.
A1 Winzeler, Elizabeth A.
T1 Global analysis of transcript and protein levels across the Plasmodium falciparum life cycle
JF Genome Research 
JO Genome Research 
YR 2004 
FD November 01 
VO 14 
IS 11 
SP 2308 
OP 2318 
DO 10.1101/gr.2523904 
UL http://genome.cshlp.org/content/14/11/2308.abstract 
AB To investigate the role of post-transcriptional controls in the regulation of protein expression for the malaria parasite, Plasmodium falciparum, we have compared mRNA transcript and protein abundance levels for seven different stages of the parasite life cycle. A moderately high positive relationship between mRNA and protein abundance was observed for these stages; the most common discrepancy was a delay between mRNA and protein accumulation. Potentially post-transcriptionally regulated genes are identified, and families of functionally related genes were observed to share similar patterns of mRNA and protein accumulation.