RT Journal
A1 Huntley, Derek
A1 Hummerich, Holger
A1 Smedley, Damian
A1 Kittivoravitkul, Sasivimol
A1 McCarthy, Mark
A1 Little, Peter
A1 Sergot, Marek
T1 GANESH: Software for Customized Annotation of Genome Regions
JF Genome Research 
JO Genome Research 
YR 2003 
FD September 01 
VO 13 
IS 9 
SP 2195 
OP 2202 
DO 10.1101/gr.698103 
UL http://genome.cshlp.org/content/13/9/2195.abstract 
AB GANESH is a software package designed to support the genetic analysis of  regions of human and other genomes. It provides a set of components that may  be assembled to construct a self-updating database of DNA sequence, mapping  data, and annotations of possible genome features. Once one or more remote  sources of data for the target region have been identified, all sequences for  that region are downloaded, assimilated, and subjected to a (configurable) set  of standard database-searching and genome-analysis packages. The results are  stored in compressed form in a relational database, and are updated  automatically on a regular schedule so that they are always immediately  available in their most up-to-date versions. A Java front-end, executed as a  stand alone application or web applet, provides a graphical interface for  navigating the database and for viewing the annotations. There are facilities  for importing and exporting data in the format of the Distributed Annotation  System (DAS), enabling a GANESH database to be used as a component of a DAS  configuration. The system has been used to construct databases for about a  dozen regions of human chromosomes and for three regions of mouse  chromosomes.