RT Journal
A1 Schriml, Lynn M.
A1 Hill, David P.
A1 Blake, Judith A.
A1 Bono, Hidemasa
A1 Wynshaw-Boris, Anthony
A1 Pavan, William J.
A1 Ring, Brian Z.
A1 Beisel, Kirk
A1 Setou, Mitsutoshi
A1 RIKEN GER Group
A1 GSL Members
A1 Okazaki, Yasushi
T1 Human Disease Genes and Their Cloned Mouse Orthologs: Exploration of the FANTOM2 cDNA Sequence Data Set
JF Genome Research 
JO Genome Research 
YR 2003 
FD June 01 
VO 13 
IS 6b 
SP 1496 
OP 1500 
DO 10.1101/gr.979503 
UL http://genome.cshlp.org/content/13/6b/1496.abstract 
AB The FANTOM2 cDNA sequence data set is an excellent model to demonstrate the  power of large-scale cDNA sequencing, with the goal of providing a full-length  transcript sequence for each mouse gene. This data set enhances the use of the  mouse as a model for human disease. Here we identify mouse cDNA sequences in  the FANTOM2 data set for a set of 67 human disease genes that as of May 2002  had no corresponding mouse cDNA annotated in the Mouse Genome Informatics  (MGI) database. These 67 human disease genes include genes related to  neurological and eye disorders and cancer. We also present a list of the human  disease genes and their cloned mouse orthologs found in two public databases,  LocusLink and MGI. Allelic variant and gene functional information available  in MGI provides additional information relative to these mouse models, whereas  computed sequence-based connections at NCBI support facile navigation through  multiple genomes.