@article{Nikaido01062003,
author = {Nikaido, Itoshi and Saito, Chika and Mizuno, Yosuke and Meguro, Makiko and Bono, Hidemasa and Kadomura, Moritoshi and Kono, Tomohiro and Morris, Gerard A. and Lyons, Paul A. and Oshimura, Mitsuo and RIKEN GER Group and GSL Members and Hayashizaki, Yoshihide and Okazaki, Yasushi}, 
title = {Discovery of Imprinted Transcripts in the Mouse Transcriptome Using Large-Scale Expression Profiling},
volume = {13}, 
number = {6b}, 
pages = {1402-1409}, 
year = {2003}, 
doi = {10.1101/gr.1055303}, 
abstract ={Candidate imprinted transcriptional units in the mouse genome were  identified systematically from 27,663 FANTOM2 full-length mouse cDNA clones by  expression profiling. Large-scale cDNA microarrays were used to detect  differential expression dependent upon chromosomal parent of origin by  comparing the mRNA levels in the total tissue of 9.5 dpc parthenogenote and  androgenote mouse embryos. Of the FANTOM2 transcripts, 2114 were identified as  candidates on the basis of the array data. Of these, 39 mapped to known  imprinted regions of the mouse genome, 56 were considered as nonprotein-coding  RNAs, and 159 were natural antisense transcripts. The imprinted expression of  two transcripts located in the mouse chromosomal region syntenic to the human  Prader-Willi syndrome region was confirmed experimentally. We further mapped  all candidate imprinted transcripts to the mouse and human genome and were  shown in correlation with the imprinting disease loci. These data provide a  major resource for understanding the role of imprinting in mammalian inherited  traits.}, 
URL = {http://genome.cshlp.org/content/13/6b/1402.abstract}, 
eprint = {http://genome.cshlp.org/content/13/6b/1402.full.pdf+html}, 
journal = {Genome Research} 
}