TY - JOUR A1 - O'Brien, Timothy P. A1 - Bult, Carol J. A1 - Cremer, Christoph A1 - Grunze, Michael A1 - Knowles, Barbara B. A1 - Langowski, Jörg A1 - McNally, James A1 - Pederson, Thoru A1 - Politz, Joan C. A1 - Pombo, Ana A1 - Schmahl, Günter A1 - Spatz, Joachim P. A1 - van Driel, Roel T1 - Genome Function and Nuclear Architecture: From Gene Expression to Nanoscience Y1 - 2003/06/01 JF - Genome Research JO - Genome Research SP - 1029 EP - 1041 DO - 10.1101/gr.946403 VL - 13 IS - 6a UR - http://genome.cshlp.org/content/13/6a/1029.abstract N2 - Biophysical, chemical, and nanoscience approaches to the study of nuclear structure and activity have been developing recently and hold considerable promise. A selection of fundamental problems in genome organization and function are reviewed and discussed in the context of these new perspectives and approaches. Advancing these concepts will require coordinated networks of physicists, chemists, and materials scientists collaborating with cell, developmental, and genome biologists. ER -