@article{O'Brien01062003, author = {O'Brien, Timothy P. and Bult, Carol J. and Cremer, Christoph and Grunze, Michael and Knowles, Barbara B. and Langowski, Jörg and McNally, James and Pederson, Thoru and Politz, Joan C. and Pombo, Ana and Schmahl, Günter and Spatz, Joachim P. and van Driel, Roel}, title = {Genome Function and Nuclear Architecture: From Gene Expression to Nanoscience}, volume = {13}, number = {6a}, pages = {1029-1041}, year = {2003}, doi = {10.1101/gr.946403}, abstract ={Biophysical, chemical, and nanoscience approaches to the study of nuclear structure and activity have been developing recently and hold considerable promise. A selection of fundamental problems in genome organization and function are reviewed and discussed in the context of these new perspectives and approaches. Advancing these concepts will require coordinated networks of physicists, chemists, and materials scientists collaborating with cell, developmental, and genome biologists.}, URL = {http://genome.cshlp.org/content/13/6a/1029.abstract}, eprint = {http://genome.cshlp.org/content/13/6a/1029.full.pdf+html}, journal = {Genome Research} }