RT Journal
A1 Giardine, Belinda
A1 Elnitski, Laura
A1 Riemer, Cathy
A1 Makalowska, Izabela
A1 Schwartz, Scott
A1 Miller, Webb
A1 Hardison, Ross C.
T1 GALA, a Database for Genomic Sequence Alignments and Annotations
JF Genome Research 
JO Genome Research 
YR 2003 
FD April 01 
VO 13 
IS 4 
SP 732 
OP 741 
DO 10.1101/gr.603103 
UL http://genome.cshlp.org/content/13/4/732.abstract 
AB We have developed a relational database to contain whole genome sequence alignments between human and mouse with extensive annotations of the human sequence. Complex queries are supported on recorded features, both directly and on proximity among them. Searches can reveal a wide variety of relationships, such as finding all genes expressed in a designated tissue that have a highly conserved noncoding sequence 5′ to the start site. Other examples are finding single nucleotide polymorphisms that occur in conserved noncoding regions upstream of genes and identifying CpG islands that overlap the 5′ ends of divergently transcribed genes. The database is available online athttp://globin.cse.psu.edu/ and http://bio.cse.psu.edu/.