TY - JOUR A1 - Gotoh, Koshichi A1 - Oishi, Michio T1 - Screening of Gene-Associated Polymorphisms by Use of In-Gel Competitive Reassociation and EST (cDNA) Array Hybridization Y1 - 2003/03/01 JF - Genome Research JO - Genome Research SP - 492 EP - 495 DO - 10.1101/gr.434103 VL - 13 IS - 3 UR - http://genome.cshlp.org/content/13/3/492.abstract N2 - In-gel competitive reassociation (IGCR) is a method of differential subtraction to enrich polymorphic DNA restriction fragments between two DNA samples without probes or specific sequence information. Here, we show that by combining IGCR and expressed sequence tags (EST) array hybridization, polymorphic DNA fragments associated with genes in complex higher organisms (Arabidopsis thaliana) can be effectively screened, demonstrating that this procedure offers a simple and efficient way to obtain gene-associated polymorphic DNA markers.[The following individuals kindly provided reagents, samples, or unpublished information as indicated in the paper: N. Sakurai, D. Shibata, and C. Kuwata.] ER -